Exportin-inspired artificial cell nuclear-exporting nanosystems

Inspired by the structural and chemical features of naturally occurring importin/exportin that allows them to pass through the nuclear pore complexes, we successfully developed an artificial nuclear-exporting nanosystem capable of eliminating compounds accumulated abnormally in the nucleus.

Detalles Bibliográficos
Autores principales: Inui, Mitsuo, Hamada, Yuta, Sejima, Nana, Ueda, Natsumi, Katayama, Tokitaka, Ono, Kimika, Nagahama, Koji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9419527/
https://www.ncbi.nlm.nih.gov/pubmed/36132290
http://dx.doi.org/10.1039/d2na00050d
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author Inui, Mitsuo
Hamada, Yuta
Sejima, Nana
Ueda, Natsumi
Katayama, Tokitaka
Ono, Kimika
Nagahama, Koji
author_facet Inui, Mitsuo
Hamada, Yuta
Sejima, Nana
Ueda, Natsumi
Katayama, Tokitaka
Ono, Kimika
Nagahama, Koji
author_sort Inui, Mitsuo
collection PubMed
description Inspired by the structural and chemical features of naturally occurring importin/exportin that allows them to pass through the nuclear pore complexes, we successfully developed an artificial nuclear-exporting nanosystem capable of eliminating compounds accumulated abnormally in the nucleus.
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spelling pubmed-94195272022-09-20 Exportin-inspired artificial cell nuclear-exporting nanosystems Inui, Mitsuo Hamada, Yuta Sejima, Nana Ueda, Natsumi Katayama, Tokitaka Ono, Kimika Nagahama, Koji Nanoscale Adv Chemistry Inspired by the structural and chemical features of naturally occurring importin/exportin that allows them to pass through the nuclear pore complexes, we successfully developed an artificial nuclear-exporting nanosystem capable of eliminating compounds accumulated abnormally in the nucleus. RSC 2022-05-12 /pmc/articles/PMC9419527/ /pubmed/36132290 http://dx.doi.org/10.1039/d2na00050d Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Chemistry
Inui, Mitsuo
Hamada, Yuta
Sejima, Nana
Ueda, Natsumi
Katayama, Tokitaka
Ono, Kimika
Nagahama, Koji
Exportin-inspired artificial cell nuclear-exporting nanosystems
title Exportin-inspired artificial cell nuclear-exporting nanosystems
title_full Exportin-inspired artificial cell nuclear-exporting nanosystems
title_fullStr Exportin-inspired artificial cell nuclear-exporting nanosystems
title_full_unstemmed Exportin-inspired artificial cell nuclear-exporting nanosystems
title_short Exportin-inspired artificial cell nuclear-exporting nanosystems
title_sort exportin-inspired artificial cell nuclear-exporting nanosystems
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9419527/
https://www.ncbi.nlm.nih.gov/pubmed/36132290
http://dx.doi.org/10.1039/d2na00050d
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AT katayamatokitaka exportininspiredartificialcellnuclearexportingnanosystems
AT onokimika exportininspiredartificialcellnuclearexportingnanosystems
AT nagahamakoji exportininspiredartificialcellnuclearexportingnanosystems

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