Noncontact tip-enhanced Raman spectroscopy for nanomaterials and biomedical applications

Tip-enhanced Raman spectroscopy (TERS) has been established as one the most efficient analytical techniques for probing vibrational states with nanoscale resolution. While TERS may be a source of unique information about chemical structure and interactions, it has a limited use for materials with ro...

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Detalles Bibliográficos
Autores principales: Voylov, Dmitry N., Bocharova, Vera, Lavrik, Nickolay V., Vlassiouk, Ivan, Polizos, Georgios, Volodin, Alexei, Shulga, Yury M., Kisliuk, Alexander, Thiyagarajan, Thirumagal, Miller, Duane D., Narayanan, Ramesh, Sumpter, Bobby G., Sokolov, Alexei P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9419720/
https://www.ncbi.nlm.nih.gov/pubmed/36133556
http://dx.doi.org/10.1039/c9na00322c
Descripción
Sumario:Tip-enhanced Raman spectroscopy (TERS) has been established as one the most efficient analytical techniques for probing vibrational states with nanoscale resolution. While TERS may be a source of unique information about chemical structure and interactions, it has a limited use for materials with rough or sticky surfaces. Development of the TERS approach utilizing a non-contact scanning probe microscopy mode can significantly extend the number of applications. Here we demonstrate a proof of the concept and feasibility of a non-contact TERS approach and test it on various materials. Our experiments show that non-contact TERS can provide 10 nm spatial resolution and a Raman signal enhancement factor of 10(5), making it very promising for chemical imaging of materials with high aspect ratio surface patterns and biomaterials.

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