Cell-imprinted substrates: in search of nanotopographical fingerprints that guide stem cell differentiation

Cell-imprinted substrates direct stem cell differentiation into various lineages, suggesting the idea of lineage-specific nanotopography. We herein examined the surface topography of five different imprinted cell patterns using AFM imaging and statistical analysis of amplitude, spatial, and hybrid r...

Descripción completa

Detalles Bibliográficos
Autores principales: Kamguyan, Khorshid, Zajforoushan Moghaddam, Saeed, Nazbar, Abolfazl, Haramshahi, Seyyed Mohammad Amin, Taheri, Shiva, Bonakdar, Shahin, Thormann, Esben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9419843/
https://www.ncbi.nlm.nih.gov/pubmed/36131729
http://dx.doi.org/10.1039/d0na00692k
Descripción
Sumario:Cell-imprinted substrates direct stem cell differentiation into various lineages, suggesting the idea of lineage-specific nanotopography. We herein examined the surface topography of five different imprinted cell patterns using AFM imaging and statistical analysis of amplitude, spatial, and hybrid roughness parameters. The results suggest that different cell imprints possess distinguished nanotopographical features.

Ejemplares similares