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Molecular dynamics simulations highlight the altered binding landscape at the spike-ACE2 interface between the Delta and Omicron variants compared to the SARS-CoV-2 original strain

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) B.1.1.529 variant (Omicron), represents a significant deviation in genetic makeup and function compared to previous variants. Following the BA.1 sublineage, the BA.2 and BA.3 Omicron subvariants became dominant, and currently the BA.4...

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Detalles Bibliográficos
Autores principales:	Pitsillou, Eleni, Liang, Julia J., Beh, Raymond C., Hung, Andrew, Karagiannis, Tom C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Ltd. 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9420038/ https://www.ncbi.nlm.nih.gov/pubmed/36055162 http://dx.doi.org/10.1016/j.compbiomed.2022.106035

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