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Bilateral Orbital Myeloid Sarcomas: A Unique Presentation of Acute Myeloid Leukemia

Myeloid sarcomas (MS) are solid manifestations of acute myeloid leukemia (AML) and are commonly present in children. These tumors can arise in many tissues including bone, soft tissue, or skin, and are commonly seen in the orbit. As practically all MS will, if left untreated, eventually present as A...

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Autores principales: Stephenson, Shane G, Barchie, Addison A, Rana, Hunaid N, Standley, Todd B, Figarola, Maria S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9420040/
https://www.ncbi.nlm.nih.gov/pubmed/36051742
http://dx.doi.org/10.7759/cureus.27419
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author Stephenson, Shane G
Barchie, Addison A
Rana, Hunaid N
Standley, Todd B
Figarola, Maria S
author_facet Stephenson, Shane G
Barchie, Addison A
Rana, Hunaid N
Standley, Todd B
Figarola, Maria S
author_sort Stephenson, Shane G
collection PubMed
description Myeloid sarcomas (MS) are solid manifestations of acute myeloid leukemia (AML) and are commonly present in children. These tumors can arise in many tissues including bone, soft tissue, or skin, and are commonly seen in the orbit. As practically all MS will, if left untreated, eventually present as AML, early diagnosis and initiation of treatment are imperative. We highlighted a case of bilateral orbital MS in a pediatric patient that presented concurrently with AML and the steps taken to diagnose and initiate treatment. Our case highlights the potentially occult presentation of AML as well as myeloid sarcoma and, therefore, the importance of swift workup and diagnosis. Epidemiology, radiographic features, diagnosis, and treatment for myeloid sarcoma and AML were discussed.
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spelling pubmed-94200402022-08-31 Bilateral Orbital Myeloid Sarcomas: A Unique Presentation of Acute Myeloid Leukemia Stephenson, Shane G Barchie, Addison A Rana, Hunaid N Standley, Todd B Figarola, Maria S Cureus Pediatrics Myeloid sarcomas (MS) are solid manifestations of acute myeloid leukemia (AML) and are commonly present in children. These tumors can arise in many tissues including bone, soft tissue, or skin, and are commonly seen in the orbit. As practically all MS will, if left untreated, eventually present as AML, early diagnosis and initiation of treatment are imperative. We highlighted a case of bilateral orbital MS in a pediatric patient that presented concurrently with AML and the steps taken to diagnose and initiate treatment. Our case highlights the potentially occult presentation of AML as well as myeloid sarcoma and, therefore, the importance of swift workup and diagnosis. Epidemiology, radiographic features, diagnosis, and treatment for myeloid sarcoma and AML were discussed. Cureus 2022-07-28 /pmc/articles/PMC9420040/ /pubmed/36051742 http://dx.doi.org/10.7759/cureus.27419 Text en Copyright © 2022, Stephenson et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Pediatrics
Stephenson, Shane G
Barchie, Addison A
Rana, Hunaid N
Standley, Todd B
Figarola, Maria S
Bilateral Orbital Myeloid Sarcomas: A Unique Presentation of Acute Myeloid Leukemia
title Bilateral Orbital Myeloid Sarcomas: A Unique Presentation of Acute Myeloid Leukemia
title_full Bilateral Orbital Myeloid Sarcomas: A Unique Presentation of Acute Myeloid Leukemia
title_fullStr Bilateral Orbital Myeloid Sarcomas: A Unique Presentation of Acute Myeloid Leukemia
title_full_unstemmed Bilateral Orbital Myeloid Sarcomas: A Unique Presentation of Acute Myeloid Leukemia
title_short Bilateral Orbital Myeloid Sarcomas: A Unique Presentation of Acute Myeloid Leukemia
title_sort bilateral orbital myeloid sarcomas: a unique presentation of acute myeloid leukemia
topic Pediatrics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9420040/
https://www.ncbi.nlm.nih.gov/pubmed/36051742
http://dx.doi.org/10.7759/cureus.27419
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