Brequinar and dipyridamole in combination exhibits synergistic antiviral activity against SARS-CoV-2 in vitro: Rationale for a host-acting antiviral treatment strategy for COVID-19

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of coronavirus disease 2019 (COVID-19) and the associated global pandemic resulting in >400 million infections worldwide and several million deaths. The continued evolution of SARS-CoV-2 to potentially evade v...

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Detalles Bibliográficos
Autores principales: Demarest, James F., Kienle, Maryline, Boytz, RuthMabel, Ayres, Mary, Kim, Eun Jung, Patten, J.J., Chung, Donghoon, Gandhi, Varsha, Davey, Robert A., Sykes, David B., Shohdy, Nadim, Pottage, John C., Kumar, Vikram S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9420051/
https://www.ncbi.nlm.nih.gov/pubmed/36041646
http://dx.doi.org/10.1016/j.antiviral.2022.105403

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