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Intracellular hemin is a potent inhibitor of the voltage-gated potassium channel Kv10.1

Heme, an iron-protoporphyrin IX complex, is a cofactor bound to various hemoproteins and supports a broad range of functions, such as electron transfer, oxygen transport, signal transduction, and drug metabolism. In recent years, there has been a growing recognition of heme as a non-genomic modulato...

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Detalles Bibliográficos
Autores principales: Sahoo, Nirakar, Yang, Kefan, Coburger, Ina, Bernert, Alisa, Swain, Sandip M., Gessner, Guido, Kappl, Reinhard, Kühl, Toni, Imhof, Diana, Hoshi, Toshinori, Schönherr, Roland, Heinemann, Stefan H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9420133/
https://www.ncbi.nlm.nih.gov/pubmed/36030326
http://dx.doi.org/10.1038/s41598-022-18975-2