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Intracellular hemin is a potent inhibitor of the voltage-gated potassium channel Kv10.1
Heme, an iron-protoporphyrin IX complex, is a cofactor bound to various hemoproteins and supports a broad range of functions, such as electron transfer, oxygen transport, signal transduction, and drug metabolism. In recent years, there has been a growing recognition of heme as a non-genomic modulato...
Autores principales: | Sahoo, Nirakar, Yang, Kefan, Coburger, Ina, Bernert, Alisa, Swain, Sandip M., Gessner, Guido, Kappl, Reinhard, Kühl, Toni, Imhof, Diana, Hoshi, Toshinori, Schönherr, Roland, Heinemann, Stefan H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9420133/ https://www.ncbi.nlm.nih.gov/pubmed/36030326 http://dx.doi.org/10.1038/s41598-022-18975-2 |
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