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Raltitrexed regulates proliferation and apoptosis of HGC-27 cells by upregulating RSK4

BACKGROUND: Raltitrexed is a specific inhibitor of thymidylate synthase and a potential chemotherapeutic agent for the treatment of advanced gastric cancer. In this study, we investigated the effect of raltitrexed on the proliferation of HGC-27 human gastric cancer cells and its potential underlying...

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Detalles Bibliográficos
Autores principales: Hu, Cong, Chen, Xinhua, Lin, Xu, Dai, Jun, Yu, Jiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9420250/
https://www.ncbi.nlm.nih.gov/pubmed/36031631
http://dx.doi.org/10.1186/s40360-022-00605-2