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Pharmaceutical and drug delivery applications of chitosan biopolymer and its modified nanocomposite: A review
Due to their improved structural and functional properties as well as biocompatibility, biodegradability, and nontoxicity, chitosan and its nanoparticles are currently grasping the interest of researchers. Although numerous attempts have been made to apply chitosan and its derivatives to biological...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9420383/ https://www.ncbi.nlm.nih.gov/pubmed/36042744 http://dx.doi.org/10.1016/j.heliyon.2022.e10196 |
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author | Kedir, Welela Meka Abdi, Gamachu Fikadu Goro, Meta Mamo Tolesa, Leta Deressa |
author_facet | Kedir, Welela Meka Abdi, Gamachu Fikadu Goro, Meta Mamo Tolesa, Leta Deressa |
author_sort | Kedir, Welela Meka |
collection | PubMed |
description | Due to their improved structural and functional properties as well as biocompatibility, biodegradability, and nontoxicity, chitosan and its nanoparticles are currently grasping the interest of researchers. Although numerous attempts have been made to apply chitosan and its derivatives to biological applications, few have reported in achieving its pharmacological and drug delivery. The goal of the current work is to provide a summary of the chitosan biopolymer's physical, chemical, and biological properties as well as its synthesis of nanoparticles and characterization of its modified nanocomposites. The drug delivery method and pharmaceutical applications of chitosan biopolymer and its modified nanocomposites are examined in further detail in this research. We will introduce also about the most current publications in this field of study as well as its recent expansion. |
format | Online Article Text |
id | pubmed-9420383 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-94203832022-08-29 Pharmaceutical and drug delivery applications of chitosan biopolymer and its modified nanocomposite: A review Kedir, Welela Meka Abdi, Gamachu Fikadu Goro, Meta Mamo Tolesa, Leta Deressa Heliyon Review Article Due to their improved structural and functional properties as well as biocompatibility, biodegradability, and nontoxicity, chitosan and its nanoparticles are currently grasping the interest of researchers. Although numerous attempts have been made to apply chitosan and its derivatives to biological applications, few have reported in achieving its pharmacological and drug delivery. The goal of the current work is to provide a summary of the chitosan biopolymer's physical, chemical, and biological properties as well as its synthesis of nanoparticles and characterization of its modified nanocomposites. The drug delivery method and pharmaceutical applications of chitosan biopolymer and its modified nanocomposites are examined in further detail in this research. We will introduce also about the most current publications in this field of study as well as its recent expansion. Elsevier 2022-08-15 /pmc/articles/PMC9420383/ /pubmed/36042744 http://dx.doi.org/10.1016/j.heliyon.2022.e10196 Text en © 2022 The Author(s) https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Article Kedir, Welela Meka Abdi, Gamachu Fikadu Goro, Meta Mamo Tolesa, Leta Deressa Pharmaceutical and drug delivery applications of chitosan biopolymer and its modified nanocomposite: A review |
title | Pharmaceutical and drug delivery applications of chitosan biopolymer and its modified nanocomposite: A review |
title_full | Pharmaceutical and drug delivery applications of chitosan biopolymer and its modified nanocomposite: A review |
title_fullStr | Pharmaceutical and drug delivery applications of chitosan biopolymer and its modified nanocomposite: A review |
title_full_unstemmed | Pharmaceutical and drug delivery applications of chitosan biopolymer and its modified nanocomposite: A review |
title_short | Pharmaceutical and drug delivery applications of chitosan biopolymer and its modified nanocomposite: A review |
title_sort | pharmaceutical and drug delivery applications of chitosan biopolymer and its modified nanocomposite: a review |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9420383/ https://www.ncbi.nlm.nih.gov/pubmed/36042744 http://dx.doi.org/10.1016/j.heliyon.2022.e10196 |
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