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Pharmaceutical and drug delivery applications of chitosan biopolymer and its modified nanocomposite: A review

Due to their improved structural and functional properties as well as biocompatibility, biodegradability, and nontoxicity, chitosan and its nanoparticles are currently grasping the interest of researchers. Although numerous attempts have been made to apply chitosan and its derivatives to biological...

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Detalles Bibliográficos
Autores principales: Kedir, Welela Meka, Abdi, Gamachu Fikadu, Goro, Meta Mamo, Tolesa, Leta Deressa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9420383/
https://www.ncbi.nlm.nih.gov/pubmed/36042744
http://dx.doi.org/10.1016/j.heliyon.2022.e10196
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author Kedir, Welela Meka
Abdi, Gamachu Fikadu
Goro, Meta Mamo
Tolesa, Leta Deressa
author_facet Kedir, Welela Meka
Abdi, Gamachu Fikadu
Goro, Meta Mamo
Tolesa, Leta Deressa
author_sort Kedir, Welela Meka
collection PubMed
description Due to their improved structural and functional properties as well as biocompatibility, biodegradability, and nontoxicity, chitosan and its nanoparticles are currently grasping the interest of researchers. Although numerous attempts have been made to apply chitosan and its derivatives to biological applications, few have reported in achieving its pharmacological and drug delivery. The goal of the current work is to provide a summary of the chitosan biopolymer's physical, chemical, and biological properties as well as its synthesis of nanoparticles and characterization of its modified nanocomposites. The drug delivery method and pharmaceutical applications of chitosan biopolymer and its modified nanocomposites are examined in further detail in this research. We will introduce also about the most current publications in this field of study as well as its recent expansion.
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spelling pubmed-94203832022-08-29 Pharmaceutical and drug delivery applications of chitosan biopolymer and its modified nanocomposite: A review Kedir, Welela Meka Abdi, Gamachu Fikadu Goro, Meta Mamo Tolesa, Leta Deressa Heliyon Review Article Due to their improved structural and functional properties as well as biocompatibility, biodegradability, and nontoxicity, chitosan and its nanoparticles are currently grasping the interest of researchers. Although numerous attempts have been made to apply chitosan and its derivatives to biological applications, few have reported in achieving its pharmacological and drug delivery. The goal of the current work is to provide a summary of the chitosan biopolymer's physical, chemical, and biological properties as well as its synthesis of nanoparticles and characterization of its modified nanocomposites. The drug delivery method and pharmaceutical applications of chitosan biopolymer and its modified nanocomposites are examined in further detail in this research. We will introduce also about the most current publications in this field of study as well as its recent expansion. Elsevier 2022-08-15 /pmc/articles/PMC9420383/ /pubmed/36042744 http://dx.doi.org/10.1016/j.heliyon.2022.e10196 Text en © 2022 The Author(s) https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review Article
Kedir, Welela Meka
Abdi, Gamachu Fikadu
Goro, Meta Mamo
Tolesa, Leta Deressa
Pharmaceutical and drug delivery applications of chitosan biopolymer and its modified nanocomposite: A review
title Pharmaceutical and drug delivery applications of chitosan biopolymer and its modified nanocomposite: A review
title_full Pharmaceutical and drug delivery applications of chitosan biopolymer and its modified nanocomposite: A review
title_fullStr Pharmaceutical and drug delivery applications of chitosan biopolymer and its modified nanocomposite: A review
title_full_unstemmed Pharmaceutical and drug delivery applications of chitosan biopolymer and its modified nanocomposite: A review
title_short Pharmaceutical and drug delivery applications of chitosan biopolymer and its modified nanocomposite: A review
title_sort pharmaceutical and drug delivery applications of chitosan biopolymer and its modified nanocomposite: a review
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9420383/
https://www.ncbi.nlm.nih.gov/pubmed/36042744
http://dx.doi.org/10.1016/j.heliyon.2022.e10196
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