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Translocation of gasdermin D induced mitochondrial injury and mitophagy mediated quality control in lipopolysaccharide related cardiomyocyte injury

BACKGROUNDS: Inflammation underlies the mechanism of different kinds of heart disease. Cytoplasmic membrane localized N‐terminal fragment of gasdermin‐D (GSDMD‐N) could induce inflammatory injury to cardiomyocyte. However, effects and dynamic changes of GSDMD during the process of lipopolysaccharide...

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Detalles Bibliográficos
Autores principales: Yu, Ziqing, Xiao, Zilong, Guan, Lichun, Bao, Pei, Yu, Yong, Liang, Yixiu, Li, Minghui, Huang, Zhenzhen, Chen, Xueying, Chen, Ruizhen, Su, Yangang, Ge, Junbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9420421/
https://www.ncbi.nlm.nih.gov/pubmed/36030524
http://dx.doi.org/10.1002/ctm2.1002