Cargando…

Rapid peptide exchange on MHC class I by small molecules elucidates dynamics of bound peptide

Complexes of peptides with recombinant major histocompatibility complex class I molecules (rpMHCs) are an important tool for T cell detection, isolation, and activation in cancer immunotherapy. The rapid preparation of rpMHCs is aided by peptide exchange, for which several technologies exist. Here,...

Descripción completa

Detalles Bibliográficos
Autores principales: Hadeler, Andries, Saikia, Ankur, Zacharias, Martin, Springer, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9420430/
https://www.ncbi.nlm.nih.gov/pubmed/36042776
http://dx.doi.org/10.1016/j.crimmu.2022.08.002