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Rapid peptide exchange on MHC class I by small molecules elucidates dynamics of bound peptide

Complexes of peptides with recombinant major histocompatibility complex class I molecules (rpMHCs) are an important tool for T cell detection, isolation, and activation in cancer immunotherapy. The rapid preparation of rpMHCs is aided by peptide exchange, for which several technologies exist. Here,...

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Detalles Bibliográficos
Autores principales:	Hadeler, Andries, Saikia, Ankur, Zacharias, Martin, Springer, Sebastian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9420430/ https://www.ncbi.nlm.nih.gov/pubmed/36042776 http://dx.doi.org/10.1016/j.crimmu.2022.08.002

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