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Recurrent Giant Cell Tumour of Distal End Radius: Treatment and Outcomes After Further Surgeries

Introduction: Distal end radius is the second most common location for giant cell tumours (GCTs) followed by the knee. Like at any other location, they are treated with extended curettage or resection but reportedly have an increased propensity for recurrence. This study aims to treat the recurrent...

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Autores principales: Yadav, Umesh, Singla, Mohit, Sheoran, Ajay, Behera, Kshitij, Garg, Abhishek, Kundu, Zile Singh, Gupta, Anand, Devgun, Ashish, Kumar, Ravi, Yadav, Puneet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9420457/
https://www.ncbi.nlm.nih.gov/pubmed/36051721
http://dx.doi.org/10.7759/cureus.27451
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author Yadav, Umesh
Singla, Mohit
Sheoran, Ajay
Behera, Kshitij
Garg, Abhishek
Kundu, Zile Singh
Gupta, Anand
Devgun, Ashish
Kumar, Ravi
Yadav, Puneet
author_facet Yadav, Umesh
Singla, Mohit
Sheoran, Ajay
Behera, Kshitij
Garg, Abhishek
Kundu, Zile Singh
Gupta, Anand
Devgun, Ashish
Kumar, Ravi
Yadav, Puneet
author_sort Yadav, Umesh
collection PubMed
description Introduction: Distal end radius is the second most common location for giant cell tumours (GCTs) followed by the knee. Like at any other location, they are treated with extended curettage or resection but reportedly have an increased propensity for recurrence. This study aims to treat the recurrent distal end radius GCTs and their outcome after further surgeries. Patients and methods: This study was conducted retrospectively from 2009 to 2021 and included 32 patients with recurrent distal end radius GCTs with a mean age of 29.53 years (range: 18-45 years). Twenty-five recurrences occurred after curettage and seven after resection. Twelve lesions were treated with further extended curettage. Nineteen recurrent lesions were treated with resection and arthrodesis. One out of two soft tissue recurrences was treated with en bloc resection. The mean follow-up period was 45.25 months (range: 24-120). Results: The patients with joint preservations treated with further curettage and those where resection of soft tissue recurrences was done with salvage of joint had better functional outcomes with a mean Musculoskeletal Tumor Society (MSTS) score of 26.53 (Range: 22-30). The cases with arthrodesis had an average score of 23.75 (Range: 20-26). The overall average MSTS score was 24.89. Conclusions: We conclude that local recurrence contained within the bone can be re-curetted. The isolated soft tissue recurrences can be re-excised. The bony lesions with extensive soft tissue extension should be treated with resection and reconstruction. The re-recurrence rate after further adequate treatment does not increase much.
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spelling pubmed-94204572022-08-31 Recurrent Giant Cell Tumour of Distal End Radius: Treatment and Outcomes After Further Surgeries Yadav, Umesh Singla, Mohit Sheoran, Ajay Behera, Kshitij Garg, Abhishek Kundu, Zile Singh Gupta, Anand Devgun, Ashish Kumar, Ravi Yadav, Puneet Cureus Oncology Introduction: Distal end radius is the second most common location for giant cell tumours (GCTs) followed by the knee. Like at any other location, they are treated with extended curettage or resection but reportedly have an increased propensity for recurrence. This study aims to treat the recurrent distal end radius GCTs and their outcome after further surgeries. Patients and methods: This study was conducted retrospectively from 2009 to 2021 and included 32 patients with recurrent distal end radius GCTs with a mean age of 29.53 years (range: 18-45 years). Twenty-five recurrences occurred after curettage and seven after resection. Twelve lesions were treated with further extended curettage. Nineteen recurrent lesions were treated with resection and arthrodesis. One out of two soft tissue recurrences was treated with en bloc resection. The mean follow-up period was 45.25 months (range: 24-120). Results: The patients with joint preservations treated with further curettage and those where resection of soft tissue recurrences was done with salvage of joint had better functional outcomes with a mean Musculoskeletal Tumor Society (MSTS) score of 26.53 (Range: 22-30). The cases with arthrodesis had an average score of 23.75 (Range: 20-26). The overall average MSTS score was 24.89. Conclusions: We conclude that local recurrence contained within the bone can be re-curetted. The isolated soft tissue recurrences can be re-excised. The bony lesions with extensive soft tissue extension should be treated with resection and reconstruction. The re-recurrence rate after further adequate treatment does not increase much. Cureus 2022-07-29 /pmc/articles/PMC9420457/ /pubmed/36051721 http://dx.doi.org/10.7759/cureus.27451 Text en Copyright © 2022, Yadav et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Oncology
Yadav, Umesh
Singla, Mohit
Sheoran, Ajay
Behera, Kshitij
Garg, Abhishek
Kundu, Zile Singh
Gupta, Anand
Devgun, Ashish
Kumar, Ravi
Yadav, Puneet
Recurrent Giant Cell Tumour of Distal End Radius: Treatment and Outcomes After Further Surgeries
title Recurrent Giant Cell Tumour of Distal End Radius: Treatment and Outcomes After Further Surgeries
title_full Recurrent Giant Cell Tumour of Distal End Radius: Treatment and Outcomes After Further Surgeries
title_fullStr Recurrent Giant Cell Tumour of Distal End Radius: Treatment and Outcomes After Further Surgeries
title_full_unstemmed Recurrent Giant Cell Tumour of Distal End Radius: Treatment and Outcomes After Further Surgeries
title_short Recurrent Giant Cell Tumour of Distal End Radius: Treatment and Outcomes After Further Surgeries
title_sort recurrent giant cell tumour of distal end radius: treatment and outcomes after further surgeries
topic Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9420457/
https://www.ncbi.nlm.nih.gov/pubmed/36051721
http://dx.doi.org/10.7759/cureus.27451
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