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Rearrangement of T Cell genome architecture regulates GVHD

WAPL, cohesin’s DNA release factor, regulates three-dimensional (3D) chromatin architecture. The 3D chromatin structure and its relevance to mature T cell functions is not well understood. We show that in vivo lymphopenic expansion, and alloantigen-driven proliferation, alters the 3D structure and f...

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Detalles Bibliográficos
Autores principales:	Sun, Yaping, Dotson, Gabrielle A., Muir, Lindsey A., Ronquist, Scott, Oravecz-Wilson, Katherine, Peltier, Daniel, Seike, Keisuke, Li, Lu, Meixner, Walter, Rajapakse, Indika, Reddy, Pavan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9420521/ https://www.ncbi.nlm.nih.gov/pubmed/36043052 http://dx.doi.org/10.1016/j.isci.2022.104846

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