A Case of Colon Cancer and Pauci-Immune Crescentic Glomerulonephritis

The association between membranous nephropathy and cancer has been well documented. Crescentic glomerulonephritis (GN) has also been associated with various types of cancers. To our knowledge, there has only been one previously documented case of seronegative pauci-immune crescentic glomerulonephrit...

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Detalles Bibliográficos
Autores principales: Wilhelm, David, Caster, Dawn, Coventry, Susan, Garg, Gunjan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Nephrology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9420541/
https://www.ncbi.nlm.nih.gov/pubmed/36060342
http://dx.doi.org/10.7759/cureus.27460
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author Wilhelm, David
Caster, Dawn
Coventry, Susan
Garg, Gunjan
author_facet Wilhelm, David
Caster, Dawn
Coventry, Susan
Garg, Gunjan
author_sort Wilhelm, David
collection PubMed
description The association between membranous nephropathy and cancer has been well documented. Crescentic glomerulonephritis (GN) has also been associated with various types of cancers. To our knowledge, there has only been one previously documented case of seronegative pauci-immune crescentic glomerulonephritis associated with colon cancer. We present a case of a 51-year-old male with newly diagnosed high-grade poorly-differentiated colon carcinoma who was found to have seronegative pauci-immune crescentic GN with 70% involvement of glomeruli on renal biopsy. The patient was treated with pulse steroids and rituximab with resolution of acute kidney injury.
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spelling pubmed-94205412022-09-01 A Case of Colon Cancer and Pauci-Immune Crescentic Glomerulonephritis Wilhelm, David Caster, Dawn Coventry, Susan Garg, Gunjan Cureus Nephrology The association between membranous nephropathy and cancer has been well documented. Crescentic glomerulonephritis (GN) has also been associated with various types of cancers. To our knowledge, there has only been one previously documented case of seronegative pauci-immune crescentic glomerulonephritis associated with colon cancer. We present a case of a 51-year-old male with newly diagnosed high-grade poorly-differentiated colon carcinoma who was found to have seronegative pauci-immune crescentic GN with 70% involvement of glomeruli on renal biopsy. The patient was treated with pulse steroids and rituximab with resolution of acute kidney injury. Cureus 2022-07-29 /pmc/articles/PMC9420541/ /pubmed/36060342 http://dx.doi.org/10.7759/cureus.27460 Text en Copyright © 2022, Wilhelm et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Nephrology
Wilhelm, David
Caster, Dawn
Coventry, Susan
Garg, Gunjan
A Case of Colon Cancer and Pauci-Immune Crescentic Glomerulonephritis
title A Case of Colon Cancer and Pauci-Immune Crescentic Glomerulonephritis
title_full A Case of Colon Cancer and Pauci-Immune Crescentic Glomerulonephritis
title_fullStr A Case of Colon Cancer and Pauci-Immune Crescentic Glomerulonephritis
title_full_unstemmed A Case of Colon Cancer and Pauci-Immune Crescentic Glomerulonephritis
title_short A Case of Colon Cancer and Pauci-Immune Crescentic Glomerulonephritis
title_sort case of colon cancer and pauci-immune crescentic glomerulonephritis
topic Nephrology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9420541/
https://www.ncbi.nlm.nih.gov/pubmed/36060342
http://dx.doi.org/10.7759/cureus.27460
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