Cargando…

Ellagic Acid as a Potential Inhibitor against the Nonstructural Protein NS3 Helicase of Zika Virus: A Molecular Modelling Study

Zika virus is a member of the Flaviviridae family and genus Flavivirus, which has a phylogenetic relationship with spondweni virus. It spreads to humans through a mosquito bite. To identify potential inhibitors for the Zika virus with biosafety, we selected natural antiviral compounds isolated from...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kullappan, Malathi, Benedict, Balakrishnan Anna, Rajajagadeesan, Anusha, Baskaran, Padmasini, Periadurai, Nanthini Devi, Ambrose, Jenifer Mallavarpu, Gandhamaneni, Sri Harshini, Nakkella, Aruna Kumari, Agarwal, Alok, Veeraraghavan, Vishnu Priya, Surapaneni, Krishna Mohan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9420600/ https://www.ncbi.nlm.nih.gov/pubmed/36046457 http://dx.doi.org/10.1155/2022/2044577

Ejemplares similares

Repurposing of potential antiviral drugs against RNA-dependent RNA polymerase of SARS-CoV-2 by computational approach
por: Gangadharan, Sivakumar, et al.
Publicado: (2022)

Comparison of Immunological Profiles of SARS-CoV-2 Variants in the COVID-19 Pandemic Trends: An Immunoinformatics Approach
por: Mallavarpu Ambrose, Jenifer, et al.
Publicado: (2021)

Structure-Based Virtual Screening of Benzaldehyde Thiosemicarbazone Derivatives against DNA Gyrase B of Mycobacterium tuberculosis
por: Kistan, Andiyappan, et al.
Publicado: (2021)

Plant-Derived Antiviral Compounds as Potential Entry Inhibitors against Spike Protein of SARS-CoV-2 Wild-Type and Delta Variant: An Integrative in SilicoApproach
por: Ambrose, Jenifer Mallavarpu, et al.
Publicado: (2022)

Green synthesis of silver nanoparticles from aqueous extract of Scutellaria barbata and coating on the cotton fabric for antimicrobial applications and wound healing activity in fibroblast cells (L929)
por: Veeraraghavan, Vishnu Priya, et al.
Publicado: (2021)

Rhaponticin suppresses osteosarcoma through the inhibition of PI3K-Akt-mTOR pathway
por: Mickymaray, Suresh, et al.
Publicado: (2021)

Bovine coronavirus nonstructural protein ns2 is a phosphoprotein
por: Cox, Graham J., et al.
Publicado: (1991)

Bluetongue Virus Nonstructural Protein NS3/NS3a Is Not Essential for Virus Replication
por: van Gennip, René G. P., et al.
Publicado: (2014)

Immunologic studies on the influenza A virus nonstructural protein NS1
Publicado: (1982)

Functional investigation of grass carp reovirus nonstructural protein NS80
por: Cai, Lin, et al.
Publicado: (2011)

The effect of glycosylation on cytotoxicity of Ibaraki virus nonstructural protein NS3
por: URATA, Maho, et al.
Publicado: (2015)

Antagonism of the complement component C4 by flavivirus nonstructural protein NS1
por: Avirutnan, Panisadee, et al.
Publicado: (2010)

Reovirus Nonstructural Protein σNS Recruits Viral RNA to Replication Organelles
por: Lee, Christopher H., et al.
Publicado: (2021)

Molecular docking of alkaloid compounds with the matrix metalloproteinase 2
por: Fathima, JH Shazia, et al.
Publicado: (2021)

Molecular docking analysis of SARS-CoV-2 linked RNA dependent RNA polymerase (RdRp) with compounds from Plectranthus amboinicus
por: Selvaraj, Jayaraman, et al.
Publicado: (2021)

Nonstructural proteins NS7b and NS8 are likely to be phylogenetically associated with evolution of 2019-nCoV
por: Fahmi, Muhamad, et al.
Publicado: (2020)

Nonstructural N- and C-tails of Dbp2 confer the protein full helicase activities
por: Song, Qin-Xia, et al.
Publicado: (2023)

Molecular docking data of E3 ubiquitin-protein ligase WWP1 with compounds from a medicinal plant Justicia adhatoda L
por: Selvaraj, Jayaraman, et al.
Publicado: (2021)

Stability of Dengue 2 Nonstructural Glycoprotein 1 (NS1) Is Affected by the Nature of Basic Residue at Position NS1-324
por: Ogire, Eva, et al.
Publicado: (2023)

Nonstructural Protein NS80 Is Crucial in Recruiting Viral Components to Form Aquareoviral Factories
por: Ke, Fei, et al.
Publicado: (2013)

Structure of NS3 helicase from Zika virus
por: Jain, Rinku, et al.
Publicado: (2016)

Molecular modeling of cornulin (CRNN) for docking with phytocompounds from Justicia adhatoda L.
por: Selvaraj, Jayaraman, et al.
Publicado: (2021)

Molecular docking of potential inhibitors with the mTOR protein
por: Fathima, JH Shazia, et al.
Publicado: (2021)

The nonstructural protein 2C of Coxsackie B virus has RNA helicase and chaperoning activities
por: Chen, Ziyu, et al.
Publicado: (2022)

Dengue Virus NS4b N-Terminus Disordered Region Interacts with NS3 Helicase C-Terminal Subdomain to Enhance Helicase Activity
por: Kundharapu, Satyamurthy, et al.
Publicado: (2022)

RNA Unwinding by NS3 Helicase: A Statistical Approach
por: Arunajadai, Srikesh G.
Publicado: (2009)

Molecular docking and simulation of Zika virus NS3 helicase
por: Badshah, Syed Lal, et al.
Publicado: (2019)

Hepatitis C Viral NS3-4A Protease Activity Is Enhanced by the NS3 Helicase
por: Beran, Rudolf K. F., et al.
Publicado: (2008)

Zika virus NS3 is a canonical RNA helicase stimulated by NS5 RNA polymerase
por: Xu, Shan, et al.
Publicado: (2019)

Impact of COVID-19 Vaccination on Seroprevalence of SARS-CoV-2 among the Health Care Workers in a Tertiary Care Centre, South India
por: Elangovan, Divyaa, et al.
Publicado: (2022)

The Hepatitis C Virus Nonstructural Protein 2 (NS2): An Up-and-Coming Antiviral Drug Target
por: Lorenz, Ivo C.
Publicado: (2010)

Flavivirus Nonstructural Protein NS5 Dysregulates HSP90 to Broadly Inhibit JAK/STAT Signaling
por: Roby, Justin A., et al.
Publicado: (2020)

Hepatitis C virus nonstructural protein NS3 unfolds viral G-quadruplex RNA structures
por: Belachew, Binyam, et al.
Publicado: (2022)

Effectiveness of ellagic acid on isoniazid-rifampicin induced liver damage in rats
por: Ambrose, Samuel Stephen, et al.
Publicado: (2013)

Crystal structure of the NS3-like helicase from Alongshan virus
por: Gao, Xiaopan, et al.
Publicado: (2020)

NS3 helicase inhibitory potential of the marine sponge Spongia irregularis
por: Abdelaleem, Enas Reda, et al.
Publicado: (2022)

Insights into the product release mechanism of dengue virus NS3 helicase
por: Adler, Natalia S, et al.
Publicado: (2022)

Avian reovirus-triggered apoptosis enhances both virus spread and the processing of the viral nonstructural muNS protein
por: Rodríguez-Grille, Javier, et al.
Publicado: (2014)

Human Enterovirus Nonstructural Protein 2C(ATPase) Functions as Both an RNA Helicase and ATP-Independent RNA Chaperone
por: Xia, Hongjie, et al.
Publicado: (2015)

Delayed and highly specific antibody response to nonstructural protein 1 (NS1) revealed during natural human ZIKV infection by NS1-based capture ELISA
por: Gao, Xiujie, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_qj9m9d1frplba2c4c8rv9ffamp