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Efficacy of Hydroxychloroquine for Improving Pregnancy Outcomes in a Female with Systemic Lupus Erythematosus and Antiphospholipid Syndrome
The use of heparin and low-dose aspirin is the current conventional treatment for pregnant females with antiphospholipid syndrome (APS). However, there is no additional treatment recommended for cases where the standard treatment cannot prevent obstetric complications such as fetal loss and placenta...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9420616/ https://www.ncbi.nlm.nih.gov/pubmed/36046125 http://dx.doi.org/10.1155/2022/5612091 |
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author | Takaki, Yumika Daimon, Atsushi Nunode, Misa Tanaka, Tomohito Fujita, Daisuke Ohmichi, Masahide |
author_facet | Takaki, Yumika Daimon, Atsushi Nunode, Misa Tanaka, Tomohito Fujita, Daisuke Ohmichi, Masahide |
author_sort | Takaki, Yumika |
collection | PubMed |
description | The use of heparin and low-dose aspirin is the current conventional treatment for pregnant females with antiphospholipid syndrome (APS). However, there is no additional treatment recommended for cases where the standard treatment cannot prevent obstetric complications such as fetal loss and placental insufficiency. Recently, the addition of a novel antimalarial, hydroxychloroquine (HCQ), to the conventional treatment has shown the potential to prevent obstetric complications. Herein, we report a case in which the addition of HCQ improved adverse pregnancy outcomes in a pregnant female with systemic lupus erythematosus and aspirin-heparin-resistant APS. |
format | Online Article Text |
id | pubmed-9420616 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-94206162022-08-30 Efficacy of Hydroxychloroquine for Improving Pregnancy Outcomes in a Female with Systemic Lupus Erythematosus and Antiphospholipid Syndrome Takaki, Yumika Daimon, Atsushi Nunode, Misa Tanaka, Tomohito Fujita, Daisuke Ohmichi, Masahide Case Rep Obstet Gynecol Case Report The use of heparin and low-dose aspirin is the current conventional treatment for pregnant females with antiphospholipid syndrome (APS). However, there is no additional treatment recommended for cases where the standard treatment cannot prevent obstetric complications such as fetal loss and placental insufficiency. Recently, the addition of a novel antimalarial, hydroxychloroquine (HCQ), to the conventional treatment has shown the potential to prevent obstetric complications. Herein, we report a case in which the addition of HCQ improved adverse pregnancy outcomes in a pregnant female with systemic lupus erythematosus and aspirin-heparin-resistant APS. Hindawi 2022-08-21 /pmc/articles/PMC9420616/ /pubmed/36046125 http://dx.doi.org/10.1155/2022/5612091 Text en Copyright © 2022 Yumika Takaki et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Takaki, Yumika Daimon, Atsushi Nunode, Misa Tanaka, Tomohito Fujita, Daisuke Ohmichi, Masahide Efficacy of Hydroxychloroquine for Improving Pregnancy Outcomes in a Female with Systemic Lupus Erythematosus and Antiphospholipid Syndrome |
title | Efficacy of Hydroxychloroquine for Improving Pregnancy Outcomes in a Female with Systemic Lupus Erythematosus and Antiphospholipid Syndrome |
title_full | Efficacy of Hydroxychloroquine for Improving Pregnancy Outcomes in a Female with Systemic Lupus Erythematosus and Antiphospholipid Syndrome |
title_fullStr | Efficacy of Hydroxychloroquine for Improving Pregnancy Outcomes in a Female with Systemic Lupus Erythematosus and Antiphospholipid Syndrome |
title_full_unstemmed | Efficacy of Hydroxychloroquine for Improving Pregnancy Outcomes in a Female with Systemic Lupus Erythematosus and Antiphospholipid Syndrome |
title_short | Efficacy of Hydroxychloroquine for Improving Pregnancy Outcomes in a Female with Systemic Lupus Erythematosus and Antiphospholipid Syndrome |
title_sort | efficacy of hydroxychloroquine for improving pregnancy outcomes in a female with systemic lupus erythematosus and antiphospholipid syndrome |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9420616/ https://www.ncbi.nlm.nih.gov/pubmed/36046125 http://dx.doi.org/10.1155/2022/5612091 |
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