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Deep mutational scanning identifies SARS-CoV-2 Nucleocapsid escape mutations of currently available rapid antigen tests

The effects of mutations in continuously emerging variants of SARS-CoV-2 are a major concern for the performance of rapid antigen tests. To evaluate the impact of mutations on 17 antibodies used in 11 commercially available antigen tests with emergency use authorization, we measured antibody binding...

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Detalles Bibliográficos
Autores principales: Frank, Filipp, Keen, Meredith M., Rao, Anuradha, Bassit, Leda, Liu, Xu, Bowers, Heather B., Patel, Anamika B., Cato, Michael L., Sullivan, Julie A., Greenleaf, Morgan, Piantadosi, Anne, Lam, Wilbur A., Hudson, William H., Ortlund, Eric A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9420710/
https://www.ncbi.nlm.nih.gov/pubmed/36084631
http://dx.doi.org/10.1016/j.cell.2022.08.010