Model-Predicted Impact of ECG Monitoring Strategies During Bedaquiline Treatment

BACKGROUND: The M2 metabolite of bedaquiline causes QT-interval prolongation, making electrocardiogram (ECG) monitoring of patients receiving bedaquiline for drug-resistant tuberculosis necessary. The objective of this study was to determine the relationship between M2 exposure and Fridericia-correc...

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Detalles Bibliográficos
Autores principales: van Beek, Stijn W, Tanneau, Lénaïg, Meintjes, Graeme, Wasserman, Sean, Gandhi, Neel R, Campbell, Angie, Viljoen, Charle A, Wiesner, Lubbe, Aarnoutse, Rob E, Maartens, Gary, Brust, James C M, Svensson, Elin M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Major Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9420883/
https://www.ncbi.nlm.nih.gov/pubmed/36043179
http://dx.doi.org/10.1093/ofid/ofac372

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9420883/
https://www.ncbi.nlm.nih.gov/pubmed/36043179
http://dx.doi.org/10.1093/ofid/ofac372

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