Cargando…

Single-cell RNA sequencing reveals the cellular and molecular changes that contribute to the progression of lung adenocarcinoma

Pure ground glass nodules (GGNs) and solid nodules (SNs) represent early and relatively late stages of lung adenocarcinoma (LUAD) in radiology, respectively. The cellular and molecular characteristics of pure GGNs and SNs have not been comprehensively elucidated. Additionally, the mechanism driving...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Bing, Wang, Chen, Fang, Zhanjie, Bai, Jing, Qian, Ying, Ma, Yuanyuan, Ruan, Xiuyan, Yan, Shi, Li, Shaolei, Wang, Yaqi, Dong, Bin, Yang, Xin, Li, Meng, Xia, Xuefeng, Qu, Hongzhu, Fang, Xiangdong, Wu, Nan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9420948/ https://www.ncbi.nlm.nih.gov/pubmed/36046337 http://dx.doi.org/10.3389/fcell.2022.927300

Ejemplares similares

Comprehensive Analysis Uncovers Prognostic and Immunogenic Characteristics of Cellular Senescence for Lung Adenocarcinoma
por: Lin, Weihao, et al.
Publicado: (2021)

Transport Pathways That Contribute to the Cellular Distribution of Phosphatidylserine
por: Lenoir, Guillaume, et al.
Publicado: (2021)

Predictive Value of Max’s Giant Associated Protein Mutation in Outcomes of Lung Adenocarcinoma Patients Treated With Immune Checkpoint Inhibitors
por: Qu, Yan, et al.
Publicado: (2021)

Differential Cellular Stiffness Contributes to Tissue Elongation on an Expanding Surface
por: Koyama, Hiroshi, et al.
Publicado: (2022)

Potential Role of Cellular Senescence in Asthma
por: Wang, Zhao-Ni, et al.
Publicado: (2020)

More than Just a Simple Cardiac Envelope; Cellular Contributions of the Epicardium
por: Dueñas, Angel, et al.
Publicado: (2017)

The Cellular Origins of Cancer-Associated Fibroblasts and Their Opposing Contributions to Pancreatic Cancer Growth
por: Manoukian, Paul, et al.
Publicado: (2021)

The Combined Contribution of Vascular Endothelial Cell Migration and Adhesion to Stent Re-endothelialization
por: Wang, Xiaoli, et al.
Publicado: (2021)

Single-Cell Analysis Reveals Spatial Heterogeneity of Immune Cells in Lung Adenocarcinoma
por: Wang, Youyu, et al.
Publicado: (2021)

Hypoxia Constructing the Prognostic Model of Colorectal Adenocarcinoma and Related to the Immune Microenvironment
por: Zhang, Yuanyuan, et al.
Publicado: (2021)

Dynamic Epicardial Contribution to Cardiac Interstitial c-Kit and Sca1 Cellular Fractions
por: Pogontke, C., et al.
Publicado: (2022)

KLF2 Inhibits Chicken Preadipocyte Differentiation at Least in Part via Directly Repressing PPARγ Transcript Variant 1 Expression
por: Cui, Tingting, et al.
Publicado: (2021)

Role of RNA N6-Methyladenosine Modification in Male Infertility and Genital System Tumors
por: Liu, Shuai, et al.
Publicado: (2021)

Prognostic Value of Genomic Instability of m(6)A-Related lncRNAs in Lung Adenocarcinoma
por: Li, Rui, et al.
Publicado: (2022)

Histone methyltransferase KMT2D contributes to the protection of myocardial ischemic injury
por: Liu, Shu-Bao, et al.
Publicado: (2022)

Transcriptional Activation of Matricellular Protein Spondin2 (SPON2) by BRG1 in Vascular Endothelial Cells Promotes Macrophage Chemotaxis
por: Li, Nan, et al.
Publicado: (2020)

Corrigendum: Transcriptional Activation of Matricellular Protein Spondin2 (SPON2) by BRG1 in Vascular Endothelial Cells Promotes Macrophage Chemotaxis
por: Li, Nan, et al.
Publicado: (2021)

Glycolysis Define Two Prognostic Subgroups of Lung Adenocarcinoma With Different Mutation Characteristics and Immune Infiltration Signatures
por: Huo, Chen, et al.
Publicado: (2021)

Mucus Hypersecretion and Ciliary Impairment in Conducting Airway Contribute to Alveolar Mucus Plugging in Idiopathic Pulmonary Fibrosis
por: Peng, Yang, et al.
Publicado: (2022)

Upregulation of SPP1 Is a Marker for Poor Lung Cancer Prognosis and Contributes to Cancer Progression and Cisplatin Resistance
por: Tang, Huaping, et al.
Publicado: (2021)

Microtubule Severing Protein Fignl2 Contributes to Endothelial and Neuronal Branching in Zebrafish Development
por: Dong, Zhangji, et al.
Publicado: (2021)

Development of Tumor Mutation Burden-Related Prognostic Model and Novel Biomarker Identification in Stomach Adenocarcinoma
por: Fu, Min, et al.
Publicado: (2022)

Krüppel-Like Factor 15 Modulates CXCL1/CXCR2 Signaling-Mediated Inflammatory Response Contributing to Angiotensin II-Induced Cardiac Remodeling
por: He, Shun, et al.
Publicado: (2021)

Prognostic Nomograms Based on Ground Glass Opacity and Subtype of Lung Adenocarcinoma for Patients with Pathological Stage IA Lung Adenocarcinoma
por: Zhai, Wenyu, et al.
Publicado: (2021)

Hypoxia Activates Notch4 via ERK/JNK/P38 MAPK Signaling Pathways to Promote Lung Adenocarcinoma Progression and Metastasis
por: Li, Xiaochen, et al.
Publicado: (2021)

Identification of CDK2-Related Immune Forecast Model and ceRNA in Lung Adenocarcinoma, a Pan-Cancer Analysis
por: Liu, Ting-Ting, et al.
Publicado: (2021)

An N6-Methyladenosine-Related Gene Set Variation Score as a Prognostic Tool for Lung Adenocarcinoma
por: Zhang, Huijuan, et al.
Publicado: (2021)

Long Non-coding RNA ASNR Targeting miR-519e-5p Promotes Gastric Cancer Development by Regulating FGFR2
por: Chen, Zihao, et al.
Publicado: (2021)

miR-376a Provokes Rectum Adenocarcinoma Via CTC1 Depletion-Induced Telomere Dysfunction
por: Liu, Yang, et al.
Publicado: (2021)

Multi-Omics Integrative Bioinformatics Analyses Reveal Long Non-coding RNA Modulates Genomic Integrity via Competing Endogenous RNA Mechanism and Serves as Novel Biomarkers for Overall Survival in Lung Adenocarcinoma
por: Wang, Zhonglin, et al.
Publicado: (2021)

NTNG1 Modulates Cisplatin Resistance in Epithelial Ovarian Cancer Cells via the GAS6/AXL/Akt Pathway
por: Fang, Shanyu, et al.
Publicado: (2021)

ASPH Regulates Osteogenic Differentiation and Cellular Senescence of BMSCs
por: Peng, Hui, et al.
Publicado: (2020)

Revealing Cavin-2 Gene Function in Lung Based on Multi-Omics Data Analysis Method
por: Li, Changsheng, et al.
Publicado: (2022)

Association of aging-related genes with prognosis and immune infiltration in pancreatic adenocarcinoma
por: Xue, Shengbai, et al.
Publicado: (2022)

Identification of a Five Autophagy Subtype-Related Gene Expression Pattern for Improving the Prognosis of Lung Adenocarcinoma
por: Zhang, Meng-Yu, et al.
Publicado: (2021)

Two Similar Signatures for Predicting the Prognosis and Immunotherapy Efficacy of Stomach Adenocarcinoma Patients
por: Yue, Taohua, et al.
Publicado: (2021)

Discovery of SIRT7 Inhibitor as New Therapeutic Options Against Liver Cancer
por: Zhang, Chen, et al.
Publicado: (2022)

Prognostic Nutritional Index (PNI) in Patients With Breast Cancer Treated With Neoadjuvant Chemotherapy as a Useful Prognostic Indicator
por: Chen, Li, et al.
Publicado: (2021)

Single-Cell Transcriptome Reveals the Metabolic and Clinical Features of a Highly Malignant Cell Subpopulation in Pancreatic Ductal Adenocarcinoma
por: Fang, Yangyang, et al.
Publicado: (2022)

METTL3 Contributes to Osteosarcoma Progression by Increasing DANCR mRNA Stability via m6A Modification
por: Zhou, Xinying, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_21ejphi3grkdgg4jm5rm42tojm