Interactions between heparin and SARS-CoV-2 spike glycoprotein RBD from omicron and other variants

Heparan sulfate (HS) acts as a co-receptor of angiotensin-converting enzyme 2 (ACE2) by interacting with severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) spike glycoprotein (SGP) facilitating host cell entry of SARS-CoV-2 virus. Heparin, a highly sulfated version of heparan sulfa...

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Detalles Bibliográficos
Autores principales: Gelbach, Adrianne L., Zhang, Fuming, Kwon, Seok-Joon, Bates, John T., Farmer, Andrew P., Dordick, Jonathan S., Wang, Chunyu, Linhardt, Robert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9420978/
https://www.ncbi.nlm.nih.gov/pubmed/36046608
http://dx.doi.org/10.3389/fmolb.2022.912887

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9420978/
https://www.ncbi.nlm.nih.gov/pubmed/36046608
http://dx.doi.org/10.3389/fmolb.2022.912887

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