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Multi-tissue transcriptional changes and core circadian clock disruption following intensive care

Objective: Both critical illness and current care have been hypothesized to upset daily rhythms and impair molecular circadian function. However, the influence of critical illness on clock function in different tissues and on circadian output genes are unknown. Here we evaluate the effect of critica...

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Detalles Bibliográficos
Autores principales: Hollis, Henry C., Francis, Julian N., Anafi, Ron C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9420996/
https://www.ncbi.nlm.nih.gov/pubmed/36045754
http://dx.doi.org/10.3389/fphys.2022.942704