Sex differences in the therapeutic effect of unaltered versus NFκB sensing IL-4 over-expressing mesenchymal stromal cells in a murine model of chronic inflammatory bone loss

Wear particles from joint arthroplasties induce chronic inflammation associated with prolonged upregulation of nuclear factor kappa-B (NF-κB) signaling in macrophages and osteoclasts, which leads to osteolysis and implant loosening. Mesenchymal stromal cell (MSC)-based therapy showed great potential...

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Detalles Bibliográficos
Autores principales: Shen, Huaishuang, Kushioka, Junichi, Toya, Masakazu, Utsunomiya, Takeshi, Hirata, Hirohito, Huang, Ejun Elijah, Tsubosaka, Masanori, Gao, Qi, Li, Xueping, Teissier, Victoria, Zhang, Ning, Goodman, Stuart B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Bioengineering and Biotechnology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9421000/
https://www.ncbi.nlm.nih.gov/pubmed/36046680
http://dx.doi.org/10.3389/fbioe.2022.962114

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9421000/
https://www.ncbi.nlm.nih.gov/pubmed/36046680
http://dx.doi.org/10.3389/fbioe.2022.962114

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