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Multiple genome alignment in the telomere-to-telomere assembly era

With the arrival of telomere-to-telomere (T2T) assemblies of the human genome comes the computational challenge of efficiently and accurately constructing multiple genome alignments at an unprecedented scale. By identifying nucleotides across genomes which share a common ancestor, multiple genome al...

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Detalles Bibliográficos
Autores principales: Kille, Bryce, Balaji, Advait, Sedlazeck, Fritz J., Nute, Michael, Treangen, Todd J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9421119/
https://www.ncbi.nlm.nih.gov/pubmed/36038949
http://dx.doi.org/10.1186/s13059-022-02735-6

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