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Human metapneumovirus M2-2 protein inhibits RIG-I signaling by preventing TRIM25-mediated RIG-I ubiquitination

Retinoic acid-inducible gene I (RIG-I) is a receptor that senses viral RNA and interacts with mitochondrial antiviral signaling (MAVS) protein, leading to the production of type I interferons and inflammatory cytokines to establish an antiviral state. This signaling axis is initiated by the K63-link...

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Detalles Bibliográficos
Autores principales:	Tanaka, Yukie, Morita, Naoko, Kitagawa, Yoshinori, Gotoh, Bin, Komatsu, Takayuki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9421128/ https://www.ncbi.nlm.nih.gov/pubmed/36045682 http://dx.doi.org/10.3389/fimmu.2022.970750

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