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BAC cloning and heterologous expression of a giant biosynthetic gene cluster encoding antifungal neotetrafibricin in streptomyces rubrisoli

Polyene natural products including nystatin A1, amphotericin B, ECO-02301, and mediomycin belong to a large family of valuable antifungal polyketide compounds typically produced by soil actinomycetes. A previous study (Park et al., Front. Bioeng. Biotechnol., 2021, 9, 692340) isolated Streptomyces r...

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Detalles Bibliográficos
Autores principales:	Park, Heung-Soon, Park, Ji-Hee, Kim, Hye-Jin, Kang, Seung-Hoon, Choi, Si-Sun, Kim, Eung-Soo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Bioengineering and Biotechnology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9421130/ https://www.ncbi.nlm.nih.gov/pubmed/36046673 http://dx.doi.org/10.3389/fbioe.2022.964765

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