Acute macular neuroretinopathy associated with intravitreal anti-VEGF injection: A case report

PURPOSE: to report a case of acute macular neuroretinopathy occurring after intravitreal aflibercept injection for macular edema due to CRVO. OBSERVATIONS: Two days after Aflibercept intravitreal injection, the patient developed vision loss associated with a central scotoma. Optical coherence tomogr...

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Autores principales: Radwan, Loubna M., Bou Ghanem, Ghazi O., Daye, Ghassan N., Ghazi, Nicola G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9421172/
https://www.ncbi.nlm.nih.gov/pubmed/36046518
http://dx.doi.org/10.1016/j.ajoc.2022.101687
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author Radwan, Loubna M.
Bou Ghanem, Ghazi O.
Daye, Ghassan N.
Ghazi, Nicola G.
author_facet Radwan, Loubna M.
Bou Ghanem, Ghazi O.
Daye, Ghassan N.
Ghazi, Nicola G.
author_sort Radwan, Loubna M.
collection PubMed
description PURPOSE: to report a case of acute macular neuroretinopathy occurring after intravitreal aflibercept injection for macular edema due to CRVO. OBSERVATIONS: Two days after Aflibercept intravitreal injection, the patient developed vision loss associated with a central scotoma. Optical coherence tomography showed a hyperreflective band at the level of the outer nuclear/outer plexiform layer corresponding to the patient's scotoma, ruling in the diagnosis of acute macular neuroretinopahty. Even though the OCT abnormalities resolved spontaneously, only partial resolution of the scotoma was observed 4 months later. CONCLUSIONS AND IMPORTANCE: Acute macular neuroretinopathy might be associated with intravitreal anti-VEGF injection.
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spelling pubmed-94211722022-08-30 Acute macular neuroretinopathy associated with intravitreal anti-VEGF injection: A case report Radwan, Loubna M. Bou Ghanem, Ghazi O. Daye, Ghassan N. Ghazi, Nicola G. Am J Ophthalmol Case Rep Case Report PURPOSE: to report a case of acute macular neuroretinopathy occurring after intravitreal aflibercept injection for macular edema due to CRVO. OBSERVATIONS: Two days after Aflibercept intravitreal injection, the patient developed vision loss associated with a central scotoma. Optical coherence tomography showed a hyperreflective band at the level of the outer nuclear/outer plexiform layer corresponding to the patient's scotoma, ruling in the diagnosis of acute macular neuroretinopahty. Even though the OCT abnormalities resolved spontaneously, only partial resolution of the scotoma was observed 4 months later. CONCLUSIONS AND IMPORTANCE: Acute macular neuroretinopathy might be associated with intravitreal anti-VEGF injection. Elsevier 2022-08-18 /pmc/articles/PMC9421172/ /pubmed/36046518 http://dx.doi.org/10.1016/j.ajoc.2022.101687 Text en © 2022 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Radwan, Loubna M.
Bou Ghanem, Ghazi O.
Daye, Ghassan N.
Ghazi, Nicola G.
Acute macular neuroretinopathy associated with intravitreal anti-VEGF injection: A case report
title Acute macular neuroretinopathy associated with intravitreal anti-VEGF injection: A case report
title_full Acute macular neuroretinopathy associated with intravitreal anti-VEGF injection: A case report
title_fullStr Acute macular neuroretinopathy associated with intravitreal anti-VEGF injection: A case report
title_full_unstemmed Acute macular neuroretinopathy associated with intravitreal anti-VEGF injection: A case report
title_short Acute macular neuroretinopathy associated with intravitreal anti-VEGF injection: A case report
title_sort acute macular neuroretinopathy associated with intravitreal anti-vegf injection: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9421172/
https://www.ncbi.nlm.nih.gov/pubmed/36046518
http://dx.doi.org/10.1016/j.ajoc.2022.101687
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