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Combined Effects of Tanshinone IIA and an Autophagy Inhibitor on the Apoptosis of Leukemia Cells via p53, Apoptosis-Related Proteins and Oxidative Stress Pathways

BACKGROUND: Acute myeloid leukemia (AML) is a kind of hematopoietic malignancy with limited response and acquired resistance to therapy. Inducing apoptosis and inhibiting autophagy in tumor cells is a combinational strategy for the development of anticancer therapeutics. Tanshinone IIA (TAIIA) is on...

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Detalles Bibliográficos
Autores principales:	Song, Ying-Chyi, Kuo, Cheng-Chieh, Liu, Chuan-Teng, Wu, Tsai-Chen, Kuo, Yi-Ting, Yen, Hung-Rong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9421224/ https://www.ncbi.nlm.nih.gov/pubmed/35996358 http://dx.doi.org/10.1177/15347354221117776

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