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Particularities of diagnosis in an elderly patient with neglected peritonitis: a case report
Acute peritonitis accounts for 1% of inpatient surgical emergencies and is the second leading cause of sepsis in patients in intensive care departments. Diagnosis through laboratory analysis in bacterial peritonitis focuses mainly on the biomarkers, procalcitonin and C-reactive protein. A 73-year-ol...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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SAGE Publications
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9421225/ https://www.ncbi.nlm.nih.gov/pubmed/36003024 http://dx.doi.org/10.1177/03000605221118705 |
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author | Tocu, George Tutunaru, Dana Mihailov, Raul Serban, Cristina Dimofte, Florentin Niculet, Elena Tatu, Alin Laurentiu Firescu, Dorel |
author_facet | Tocu, George Tutunaru, Dana Mihailov, Raul Serban, Cristina Dimofte, Florentin Niculet, Elena Tatu, Alin Laurentiu Firescu, Dorel |
author_sort | Tocu, George |
collection | PubMed |
description | Acute peritonitis accounts for 1% of inpatient surgical emergencies and is the second leading cause of sepsis in patients in intensive care departments. Diagnosis through laboratory analysis in bacterial peritonitis focuses mainly on the biomarkers, procalcitonin and C-reactive protein. A 73-year-old male patient presented with meteorism, diarrhea, vomiting, fever, and hypotension. Laboratory investigations showed very high procalcitonin and C-reactive protein values, and abdominal radiography revealed paraumbilical hydroaerial levels, which suggested septic shock of intra-abdominal origin. Emergency laparotomy was performed, which revealed agglutinated intestinal loops in the right iliac fossa with false membranes, purulent fluid, overdistended jejunum and ileum with an occlusive appearance, acute gangrenous appendicitis with perforation, and suppurative omentitis. The intraoperative diagnosis was acute neglected peritonitis in the occlusive phase owing to acute gangrenous appendicitis with perforation and suppurative omentitis. Laboratory analysis in conjunction with imaging provides important information in the early diagnosis of infectious pathology in elderly patients, even if these methods do not accurately identify the cause. The combination of procalcitonin and C-reactive protein biomarker levels successfully contributed to the diagnosis in this case. Notably, the patient’s white blood cell counts were inconsistent with the severity of the infection. |
format | Online Article Text |
id | pubmed-9421225 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | SAGE Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-94212252022-08-30 Particularities of diagnosis in an elderly patient with neglected peritonitis: a case report Tocu, George Tutunaru, Dana Mihailov, Raul Serban, Cristina Dimofte, Florentin Niculet, Elena Tatu, Alin Laurentiu Firescu, Dorel J Int Med Res Case Reports Acute peritonitis accounts for 1% of inpatient surgical emergencies and is the second leading cause of sepsis in patients in intensive care departments. Diagnosis through laboratory analysis in bacterial peritonitis focuses mainly on the biomarkers, procalcitonin and C-reactive protein. A 73-year-old male patient presented with meteorism, diarrhea, vomiting, fever, and hypotension. Laboratory investigations showed very high procalcitonin and C-reactive protein values, and abdominal radiography revealed paraumbilical hydroaerial levels, which suggested septic shock of intra-abdominal origin. Emergency laparotomy was performed, which revealed agglutinated intestinal loops in the right iliac fossa with false membranes, purulent fluid, overdistended jejunum and ileum with an occlusive appearance, acute gangrenous appendicitis with perforation, and suppurative omentitis. The intraoperative diagnosis was acute neglected peritonitis in the occlusive phase owing to acute gangrenous appendicitis with perforation and suppurative omentitis. Laboratory analysis in conjunction with imaging provides important information in the early diagnosis of infectious pathology in elderly patients, even if these methods do not accurately identify the cause. The combination of procalcitonin and C-reactive protein biomarker levels successfully contributed to the diagnosis in this case. Notably, the patient’s white blood cell counts were inconsistent with the severity of the infection. SAGE Publications 2022-08-24 /pmc/articles/PMC9421225/ /pubmed/36003024 http://dx.doi.org/10.1177/03000605221118705 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by-nc/4.0/Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage). |
spellingShingle | Case Reports Tocu, George Tutunaru, Dana Mihailov, Raul Serban, Cristina Dimofte, Florentin Niculet, Elena Tatu, Alin Laurentiu Firescu, Dorel Particularities of diagnosis in an elderly patient with neglected peritonitis: a case report |
title | Particularities of diagnosis in an elderly patient with neglected
peritonitis: a case report |
title_full | Particularities of diagnosis in an elderly patient with neglected
peritonitis: a case report |
title_fullStr | Particularities of diagnosis in an elderly patient with neglected
peritonitis: a case report |
title_full_unstemmed | Particularities of diagnosis in an elderly patient with neglected
peritonitis: a case report |
title_short | Particularities of diagnosis in an elderly patient with neglected
peritonitis: a case report |
title_sort | particularities of diagnosis in an elderly patient with neglected
peritonitis: a case report |
topic | Case Reports |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9421225/ https://www.ncbi.nlm.nih.gov/pubmed/36003024 http://dx.doi.org/10.1177/03000605221118705 |
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