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Metformin anticancer: Reverses tumor hypoxia induced by bevacizumab and reduces the expression of cancer stem cell markers CD44/CD117 in human ovarian cancer SKOV3 cells

Background: The occurrence and development of solid tumors depend on the blood supply in the tumor microenvironment (TME). Blocking angiogenesis is a new therapeutic strategy to inhibit tumor growth. The anti-angiogenic drug bevacizumab has been approved for gynecological malignancies, especially fo...

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Detalles Bibliográficos
Autores principales:	Fan, Yuanchun, Cheng, Huimin, Liu, Yueping, Liu, Shihao, Lowe, Scott, Li, Yaru, Bentley, Rachel, King, Bethany, Tuason, John Pocholo W., Zhou, Qin, Sun, Chenyu, Zhang, Hui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9421358/ https://www.ncbi.nlm.nih.gov/pubmed/36046821 http://dx.doi.org/10.3389/fphar.2022.955984

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