Cargando…
Monitoring extracellular ion and metabolite dynamics with recombinant nanobody-fused biosensors
Ion and analyte changes in the tumor microenvironment (TME) alter the metabolic activity of cancer cells, promote tumor cell growth, and impair anti-tumor immunity. Consequently, accurate determination and visualization of extracellular changes of analytes in real time is desired. In this study, we...
Autores principales: | Burgstaller, Sandra, Wagner, Teresa R., Bischof, Helmut, Bueckle, Sarah, Padamsey, Aman, Frecot, Desiree, Kaiser, Philipp D., Skrabak, David, Malli, Roland, Lukowski, Robert, Rothbauer, Ulrich |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9421384/ https://www.ncbi.nlm.nih.gov/pubmed/36046190 http://dx.doi.org/10.1016/j.isci.2022.104907 |
Ejemplares similares
-
30 Jahre Nanobodies: Neues von kleinen Helfern mit großem Potenzial
por: Wagner, Teresa R., et al.
Publicado: (2023) -
Unveiling the K(+)-sensitivity of cell metabolism using genetically encoded, FRET-based K(+), glucose, and ATP biosensors
por: Bischof, Helmut, et al.
Publicado: (2021) -
Immobilization of Recombinant Fluorescent Biosensors
Permits Imaging of Extracellular Ion Signals
por: Burgstaller, Sandra, et al.
Publicado: (2021) -
Investigating the K(+) sensitivity of cellular metabolism by extracellular flux analysis
por: Burgstaller, Sandra, et al.
Publicado: (2021) -
Biparatopic nanobodies protect mice from lethal challenge with SARS‐CoV‐2 variants of concern
por: Wagner, Teresa R, et al.
Publicado: (2021)