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High fructose induced osteogenic differentiation of human valve interstitial cells via activating PI3K/AKT/mitochondria signaling
BACKGROUND: Aortic valve stenosis (AS) is a common, lethal cardiovascular disease. There is no cure except the valve replacement at last stage. Therefore, an understanding of the detail mechanism is imperative to prevent and intervene AS. Metabolic syndrome (MetS) is one of the major risk factors of...
Autores principales: | Chang, Hsiao-Huang, Lin, I-Chun, Wu, Chih-Wei, Hung, Chun-Ying, Liu, Wen-Chung, Wu, Cai-Yi, Cheng, Ching-Li, Wu, Kay L.H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Chang Gung University
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9421924/ https://www.ncbi.nlm.nih.gov/pubmed/34229104 http://dx.doi.org/10.1016/j.bj.2021.06.008 |
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