Blastic plasmacytoid dendritic cell neoplasm (BPDCN) arising in the setting of polycythemia vera (PV): An illustration of the emerging role of flow cytometry analysis in monitoring progression of myeloproliferative neoplasms

This report highlights the value of flow cytometry analysis, particularly in the setting of myeloproliferative neoplasms showing features of progression, as neoplastic plasmacytoid dendritic cell (PDC) proliferations may be present, representing either a clonal expansion of mature PDCs related to th...

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Autores principales: El Hussein, Siba, Yabe, Mariko, Wang, Wei, Pemmaraju, Naveen, Loghavi, Sanam, Jelloul, Fatima Zahra, Fang, Hong, Medeiros, L. Jeffrey, Burack, W. Richard, Evans, Andrew G., Liesveld, Jane L., Bennett, John M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Short Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9421993/
https://www.ncbi.nlm.nih.gov/pubmed/36051075
http://dx.doi.org/10.1002/jha2.525
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author El Hussein, Siba
Yabe, Mariko
Wang, Wei
Pemmaraju, Naveen
Loghavi, Sanam
Jelloul, Fatima Zahra
Fang, Hong
Medeiros, L. Jeffrey
Burack, W. Richard
Evans, Andrew G.
Liesveld, Jane L.
Bennett, John M.
author_facet El Hussein, Siba
Yabe, Mariko
Wang, Wei
Pemmaraju, Naveen
Loghavi, Sanam
Jelloul, Fatima Zahra
Fang, Hong
Medeiros, L. Jeffrey
Burack, W. Richard
Evans, Andrew G.
Liesveld, Jane L.
Bennett, John M.
author_sort El Hussein, Siba
collection PubMed
description This report highlights the value of flow cytometry analysis, particularly in the setting of myeloproliferative neoplasms showing features of progression, as neoplastic plasmacytoid dendritic cell (PDC) proliferations may be present, representing either a clonal expansion of mature PDCs related to the underlying myeloproliferative neoplasm or transformation to blastic plasmacytoid dendritic cell neoplasm (BPDCN). BPDCN should always be considered in patients with myeloid neoplasms in progression and/or who develop new cutaneous findings, as it may prompt change of management.
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spelling pubmed-94219932022-08-31 Blastic plasmacytoid dendritic cell neoplasm (BPDCN) arising in the setting of polycythemia vera (PV): An illustration of the emerging role of flow cytometry analysis in monitoring progression of myeloproliferative neoplasms El Hussein, Siba Yabe, Mariko Wang, Wei Pemmaraju, Naveen Loghavi, Sanam Jelloul, Fatima Zahra Fang, Hong Medeiros, L. Jeffrey Burack, W. Richard Evans, Andrew G. Liesveld, Jane L. Bennett, John M. EJHaem Short Reports This report highlights the value of flow cytometry analysis, particularly in the setting of myeloproliferative neoplasms showing features of progression, as neoplastic plasmacytoid dendritic cell (PDC) proliferations may be present, representing either a clonal expansion of mature PDCs related to the underlying myeloproliferative neoplasm or transformation to blastic plasmacytoid dendritic cell neoplasm (BPDCN). BPDCN should always be considered in patients with myeloid neoplasms in progression and/or who develop new cutaneous findings, as it may prompt change of management. John Wiley and Sons Inc. 2022-07-03 /pmc/articles/PMC9421993/ /pubmed/36051075 http://dx.doi.org/10.1002/jha2.525 Text en © 2022 The Authors. eJHaem published by British Society for Haematology and John Wiley & Sons Ltd. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Short Reports
El Hussein, Siba
Yabe, Mariko
Wang, Wei
Pemmaraju, Naveen
Loghavi, Sanam
Jelloul, Fatima Zahra
Fang, Hong
Medeiros, L. Jeffrey
Burack, W. Richard
Evans, Andrew G.
Liesveld, Jane L.
Bennett, John M.
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) arising in the setting of polycythemia vera (PV): An illustration of the emerging role of flow cytometry analysis in monitoring progression of myeloproliferative neoplasms
title Blastic plasmacytoid dendritic cell neoplasm (BPDCN) arising in the setting of polycythemia vera (PV): An illustration of the emerging role of flow cytometry analysis in monitoring progression of myeloproliferative neoplasms
title_full Blastic plasmacytoid dendritic cell neoplasm (BPDCN) arising in the setting of polycythemia vera (PV): An illustration of the emerging role of flow cytometry analysis in monitoring progression of myeloproliferative neoplasms
title_fullStr Blastic plasmacytoid dendritic cell neoplasm (BPDCN) arising in the setting of polycythemia vera (PV): An illustration of the emerging role of flow cytometry analysis in monitoring progression of myeloproliferative neoplasms
title_full_unstemmed Blastic plasmacytoid dendritic cell neoplasm (BPDCN) arising in the setting of polycythemia vera (PV): An illustration of the emerging role of flow cytometry analysis in monitoring progression of myeloproliferative neoplasms
title_short Blastic plasmacytoid dendritic cell neoplasm (BPDCN) arising in the setting of polycythemia vera (PV): An illustration of the emerging role of flow cytometry analysis in monitoring progression of myeloproliferative neoplasms
title_sort blastic plasmacytoid dendritic cell neoplasm (bpdcn) arising in the setting of polycythemia vera (pv): an illustration of the emerging role of flow cytometry analysis in monitoring progression of myeloproliferative neoplasms
topic Short Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9421993/
https://www.ncbi.nlm.nih.gov/pubmed/36051075
http://dx.doi.org/10.1002/jha2.525
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