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Pharmacologic screen identifies active combinations with BET inhibitors and LRRK2 as a novel putative target in lymphoma
Inhibitors of the Bromo‐ and Extra‐Terminal domain (BET) family proteins have strong preclinical antitumor activity in multiple tumor models, including lymphomas. Limited single‐agent activity has been reported in the clinical setting. Here, we have performed a pharmacological screening to identify...
Autores principales: | Spriano, Filippo, Sartori, Giulio, Tarantelli, Chiara, Barreca, Marilia, Golino, Gaetanina, Rinaldi, Andrea, Napoli, Sara, Mascia, Michele, Scalise, Lorenzo, Arribas, Alberto J., Cascione, Luciano, Zucca, Emanuele, Stathis, Anastasios, Gaudio, Eugenio, Bertoni, Francesco |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9422027/ https://www.ncbi.nlm.nih.gov/pubmed/36051080 http://dx.doi.org/10.1002/jha2.535 |
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