Hematopoietic stem progenitor cells with malignancy‐related gene mutations in patients with acquired aplastic anemia are characterized by the increased expression of CXCR4

The phenotypic changes in hematopoietic stem progenitor cells (HSPCs) with somatic mutations of malignancy‐related genes in patients with acquired aplastic anemia (AA) are poorly understood. As our initial study showed increased CXCR4 expression on HLA allele‐lacking (HLA[−]) HSPCs that solely suppo...

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Detalles Bibliográficos
Autores principales: Katagiri, Takamasa, Espinoza, Jorge Luis, Uemori, Mizuho, Ikeda, Honoka, Hosokawa, Kohei, Ishiyama, Ken, Yoroidaka, Takeshi, Imi, Tatsuya, Takamatsu, Hiroyuki, Ozawa, Tatsuhiko, Kishi, Hiroyuki, Yamamoto, Yasuhiko, Elbadry, Mahmoud Ibrahim, Yoshida, Yoshinori, Chonabayashi, Kazuhisa, Takenaka, Katsuto, Akashi, Koichi, Nannya, Yasuhito, Ogawa, Seishi, Nakao, Shinji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Sickle Cell, Thrombosis, and Benign Haematology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9422028/
https://www.ncbi.nlm.nih.gov/pubmed/36051022
http://dx.doi.org/10.1002/jha2.515

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