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Molecular insights into the regulation of constitutive activity by RNA editing of 5HT(2C) serotonin receptors

RNA editing is a process by which post-transcriptional changes of mRNA nucleotides alter protein function through modification of the amino acid content. The 5HT(2C) serotonin receptor, which undergoes 32 distinct RNA-editing events leading to 24 protein isoforms, is a notable example of this proces...

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Detalles Bibliográficos
Autores principales: Gumpper, Ryan H., Fay, Jonathan F., Roth, Bryan L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9422347/
https://www.ncbi.nlm.nih.gov/pubmed/35977511
http://dx.doi.org/10.1016/j.celrep.2022.111211

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