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Functional outcomes and survival of patients with oral and oropharyngeal cancer after total glossectomy()

INTRODUCTION: Cancer of the oral cavity and oropharynx presents aggressive behavior and its diagnosis is, in most cases, performed in advanced stages. Total glossectomy is a therapeutic option in locally advanced cancer, and the only one in the recurrent or residual disease, after chemoradiotherapy....

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Autores principales: Quinsan, Isabela de Cássia Marins, Costa, Gustavo Carvalho, Priante, Antonio Vitor Martins, Cardoso, Cesar Augusto, Nunes, Caio Lúcio Soubhia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9422732/
https://www.ncbi.nlm.nih.gov/pubmed/30956152
http://dx.doi.org/10.1016/j.bjorl.2019.02.005
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author Quinsan, Isabela de Cássia Marins
Costa, Gustavo Carvalho
Priante, Antonio Vitor Martins
Cardoso, Cesar Augusto
Nunes, Caio Lúcio Soubhia
author_facet Quinsan, Isabela de Cássia Marins
Costa, Gustavo Carvalho
Priante, Antonio Vitor Martins
Cardoso, Cesar Augusto
Nunes, Caio Lúcio Soubhia
author_sort Quinsan, Isabela de Cássia Marins
collection PubMed
description INTRODUCTION: Cancer of the oral cavity and oropharynx presents aggressive behavior and its diagnosis is, in most cases, performed in advanced stages. Total glossectomy is a therapeutic option in locally advanced cancer, and the only one in the recurrent or residual disease, after chemoradiotherapy. OBJECTIVE: To evaluate the clinical-epidemiological profile, postoperative complications, survival rates and functional aspects of patients with oral cavity and oropharynx cancer after total glossectomy. METHODS: It was a retrospective study where 22 patients were included with oral cavity and oropharyngeal cancer after total glossectomy at the Hospital Regional do Vale do Paraíba, em Taubaté, São Paulo. RESULTS: All patients were male, with a median age of 57 years, most of tumors are located in the tongue and floor of the mouth and classified as stage IVa. Total glossectomy as initial treatment was performed in 18 and as salvage in four patients. The major pectoralis myocutaneous flap was used for reconstruction in all cases. The main postoperative complication was wound infection and salivary fistula. CONCLUSION: Overall survival was 19% and cancer-specific survival was 30.8% in five years. Eight patients were rehabilitated for exclusive oral feeding without the dependence tracheostomy and enteral tube, all with an overall survival greater than 15 months.
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spelling pubmed-94227322022-08-31 Functional outcomes and survival of patients with oral and oropharyngeal cancer after total glossectomy() Quinsan, Isabela de Cássia Marins Costa, Gustavo Carvalho Priante, Antonio Vitor Martins Cardoso, Cesar Augusto Nunes, Caio Lúcio Soubhia Braz J Otorhinolaryngol Original Article INTRODUCTION: Cancer of the oral cavity and oropharynx presents aggressive behavior and its diagnosis is, in most cases, performed in advanced stages. Total glossectomy is a therapeutic option in locally advanced cancer, and the only one in the recurrent or residual disease, after chemoradiotherapy. OBJECTIVE: To evaluate the clinical-epidemiological profile, postoperative complications, survival rates and functional aspects of patients with oral cavity and oropharynx cancer after total glossectomy. METHODS: It was a retrospective study where 22 patients were included with oral cavity and oropharyngeal cancer after total glossectomy at the Hospital Regional do Vale do Paraíba, em Taubaté, São Paulo. RESULTS: All patients were male, with a median age of 57 years, most of tumors are located in the tongue and floor of the mouth and classified as stage IVa. Total glossectomy as initial treatment was performed in 18 and as salvage in four patients. The major pectoralis myocutaneous flap was used for reconstruction in all cases. The main postoperative complication was wound infection and salivary fistula. CONCLUSION: Overall survival was 19% and cancer-specific survival was 30.8% in five years. Eight patients were rehabilitated for exclusive oral feeding without the dependence tracheostomy and enteral tube, all with an overall survival greater than 15 months. Elsevier 2019-03-16 /pmc/articles/PMC9422732/ /pubmed/30956152 http://dx.doi.org/10.1016/j.bjorl.2019.02.005 Text en © 2019 Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial. Published by Elsevier Editora Ltda. https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Original Article
Quinsan, Isabela de Cássia Marins
Costa, Gustavo Carvalho
Priante, Antonio Vitor Martins
Cardoso, Cesar Augusto
Nunes, Caio Lúcio Soubhia
Functional outcomes and survival of patients with oral and oropharyngeal cancer after total glossectomy()
title Functional outcomes and survival of patients with oral and oropharyngeal cancer after total glossectomy()
title_full Functional outcomes and survival of patients with oral and oropharyngeal cancer after total glossectomy()
title_fullStr Functional outcomes and survival of patients with oral and oropharyngeal cancer after total glossectomy()
title_full_unstemmed Functional outcomes and survival of patients with oral and oropharyngeal cancer after total glossectomy()
title_short Functional outcomes and survival of patients with oral and oropharyngeal cancer after total glossectomy()
title_sort functional outcomes and survival of patients with oral and oropharyngeal cancer after total glossectomy()
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9422732/
https://www.ncbi.nlm.nih.gov/pubmed/30956152
http://dx.doi.org/10.1016/j.bjorl.2019.02.005
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