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Functional outcomes and survival of patients with oral and oropharyngeal cancer after total glossectomy()
INTRODUCTION: Cancer of the oral cavity and oropharynx presents aggressive behavior and its diagnosis is, in most cases, performed in advanced stages. Total glossectomy is a therapeutic option in locally advanced cancer, and the only one in the recurrent or residual disease, after chemoradiotherapy....
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9422732/ https://www.ncbi.nlm.nih.gov/pubmed/30956152 http://dx.doi.org/10.1016/j.bjorl.2019.02.005 |
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author | Quinsan, Isabela de Cássia Marins Costa, Gustavo Carvalho Priante, Antonio Vitor Martins Cardoso, Cesar Augusto Nunes, Caio Lúcio Soubhia |
author_facet | Quinsan, Isabela de Cássia Marins Costa, Gustavo Carvalho Priante, Antonio Vitor Martins Cardoso, Cesar Augusto Nunes, Caio Lúcio Soubhia |
author_sort | Quinsan, Isabela de Cássia Marins |
collection | PubMed |
description | INTRODUCTION: Cancer of the oral cavity and oropharynx presents aggressive behavior and its diagnosis is, in most cases, performed in advanced stages. Total glossectomy is a therapeutic option in locally advanced cancer, and the only one in the recurrent or residual disease, after chemoradiotherapy. OBJECTIVE: To evaluate the clinical-epidemiological profile, postoperative complications, survival rates and functional aspects of patients with oral cavity and oropharynx cancer after total glossectomy. METHODS: It was a retrospective study where 22 patients were included with oral cavity and oropharyngeal cancer after total glossectomy at the Hospital Regional do Vale do Paraíba, em Taubaté, São Paulo. RESULTS: All patients were male, with a median age of 57 years, most of tumors are located in the tongue and floor of the mouth and classified as stage IVa. Total glossectomy as initial treatment was performed in 18 and as salvage in four patients. The major pectoralis myocutaneous flap was used for reconstruction in all cases. The main postoperative complication was wound infection and salivary fistula. CONCLUSION: Overall survival was 19% and cancer-specific survival was 30.8% in five years. Eight patients were rehabilitated for exclusive oral feeding without the dependence tracheostomy and enteral tube, all with an overall survival greater than 15 months. |
format | Online Article Text |
id | pubmed-9422732 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-94227322022-08-31 Functional outcomes and survival of patients with oral and oropharyngeal cancer after total glossectomy() Quinsan, Isabela de Cássia Marins Costa, Gustavo Carvalho Priante, Antonio Vitor Martins Cardoso, Cesar Augusto Nunes, Caio Lúcio Soubhia Braz J Otorhinolaryngol Original Article INTRODUCTION: Cancer of the oral cavity and oropharynx presents aggressive behavior and its diagnosis is, in most cases, performed in advanced stages. Total glossectomy is a therapeutic option in locally advanced cancer, and the only one in the recurrent or residual disease, after chemoradiotherapy. OBJECTIVE: To evaluate the clinical-epidemiological profile, postoperative complications, survival rates and functional aspects of patients with oral cavity and oropharynx cancer after total glossectomy. METHODS: It was a retrospective study where 22 patients were included with oral cavity and oropharyngeal cancer after total glossectomy at the Hospital Regional do Vale do Paraíba, em Taubaté, São Paulo. RESULTS: All patients were male, with a median age of 57 years, most of tumors are located in the tongue and floor of the mouth and classified as stage IVa. Total glossectomy as initial treatment was performed in 18 and as salvage in four patients. The major pectoralis myocutaneous flap was used for reconstruction in all cases. The main postoperative complication was wound infection and salivary fistula. CONCLUSION: Overall survival was 19% and cancer-specific survival was 30.8% in five years. Eight patients were rehabilitated for exclusive oral feeding without the dependence tracheostomy and enteral tube, all with an overall survival greater than 15 months. Elsevier 2019-03-16 /pmc/articles/PMC9422732/ /pubmed/30956152 http://dx.doi.org/10.1016/j.bjorl.2019.02.005 Text en © 2019 Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial. Published by Elsevier Editora Ltda. https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Original Article Quinsan, Isabela de Cássia Marins Costa, Gustavo Carvalho Priante, Antonio Vitor Martins Cardoso, Cesar Augusto Nunes, Caio Lúcio Soubhia Functional outcomes and survival of patients with oral and oropharyngeal cancer after total glossectomy() |
title | Functional outcomes and survival of patients with oral and oropharyngeal cancer after total glossectomy() |
title_full | Functional outcomes and survival of patients with oral and oropharyngeal cancer after total glossectomy() |
title_fullStr | Functional outcomes and survival of patients with oral and oropharyngeal cancer after total glossectomy() |
title_full_unstemmed | Functional outcomes and survival of patients with oral and oropharyngeal cancer after total glossectomy() |
title_short | Functional outcomes and survival of patients with oral and oropharyngeal cancer after total glossectomy() |
title_sort | functional outcomes and survival of patients with oral and oropharyngeal cancer after total glossectomy() |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9422732/ https://www.ncbi.nlm.nih.gov/pubmed/30956152 http://dx.doi.org/10.1016/j.bjorl.2019.02.005 |
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