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Temporal control of PDGFRα regulates the fibroblast-to-myofibroblast transition in wound healing
Fibroblasts differentiate into myofibroblasts by acquiring new contractile function. This is important for tissue repair, but it also contributes to organ fibrosis. Platelet-derived growth factor (PDGF) promotes tissue repair and fibrosis, but the relationship between PDGF and myofibroblasts is uncl...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9423027/ https://www.ncbi.nlm.nih.gov/pubmed/35977484 http://dx.doi.org/10.1016/j.celrep.2022.111192 |