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Temporal control of PDGFRα regulates the fibroblast-to-myofibroblast transition in wound healing

Fibroblasts differentiate into myofibroblasts by acquiring new contractile function. This is important for tissue repair, but it also contributes to organ fibrosis. Platelet-derived growth factor (PDGF) promotes tissue repair and fibrosis, but the relationship between PDGF and myofibroblasts is uncl...

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Detalles Bibliográficos
Autores principales:	Yao, Longbiao, Rathnakar, Bharath H., Kwon, Hae Ryong, Sakashita, Hiromi, Kim, Jang H., Rackley, Alex, Tomasek, James J., Berry, William L., Olson, Lorin E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9423027/ https://www.ncbi.nlm.nih.gov/pubmed/35977484 http://dx.doi.org/10.1016/j.celrep.2022.111192

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