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The prevalence of the ABCB1-1Δ variant in a clinical veterinary setting: The risk of not genotyping

Multidrug sensitivity is an autosomal recessive disorder in dogs caused by a 4-bp deletion in the ABCB1 gene, often referred to as the ABCB1-1Δ variant. This disease has a high prevalence in some breeds and causes adverse reactions to certain drugs when given in normal doses. Though most dogs known...

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Detalles Bibliográficos
Autores principales: Beckers, Evy, Casselman, Iris, Soudant, Emma, Daminet, Sylvie, Paepe, Dominique, Peelman, Luc, Broeckx, Bart J. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9423603/
https://www.ncbi.nlm.nih.gov/pubmed/36037240
http://dx.doi.org/10.1371/journal.pone.0273706

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