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Chemical and enzymatic modifications of 5-methylcytosine at the intersection of DNA damage, repair, and epigenetic reprogramming

The DNA of all living organisms is persistently damaged by endogenous reactions including deamination and oxidation. Such damage, if not repaired correctly, can result in mutations that drive tumor development. In addition to chemical damage, recent studies have established that DNA bases can be enz...

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Detalles Bibliográficos
Autores principales:	Baljinnyam, Tuvshintugs, Sowers, Mark L., Hsu, Chia Wei, Conrad, James W., Herring, Jason L., Hackfeld, Linda C., Sowers, Lawrence C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9423628/ https://www.ncbi.nlm.nih.gov/pubmed/36037209 http://dx.doi.org/10.1371/journal.pone.0273509

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