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Ultra-deep whole genome bisulfite sequencing reveals a single methylation hotspot in human brain mitochondrial DNA

While DNA methylation is established as a major regulator of gene expression in the nucleus, the existence of mitochondrial DNA (mtDNA) methylation remains controversial. Here, we characterized the mtDNA methylation landscape in the prefrontal cortex of neurological healthy individuals (n=26) and pa...

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Detalles Bibliográficos
Autores principales:	Guitton, Romain, Dölle, Christian, Alves, Guido, Ole-Bjørn, Tysnes, Nido, Gonzalo S., Tzoulis, Charalampos
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2022
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9423827/ https://www.ncbi.nlm.nih.gov/pubmed/35253628 http://dx.doi.org/10.1080/15592294.2022.2045754

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