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CXCL12 secreted by pancreatic stellate cells accelerates gemcitabine resistance of pancreatic cancer by enhancing glycolytic reprogramming

Pancreatic stellate cells (PSCs) are the primary cell components of pancreatic cancer (PC) and are involved in tumor growth, metastasis and resistance. However, the role and the mechanism of PSCs in gemcitabine (GEM) resistance to PC still need more investigation. We found that CXCL12 mRNA and secre...

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Detalles Bibliográficos
Autores principales:	Lu, Xiangyu, Wu, Yilei, Cao, Rui, Yu, Xiaojiong, Gong, Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2022
Materias:	Translational Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9423839/ https://www.ncbi.nlm.nih.gov/pubmed/36046033 http://dx.doi.org/10.1080/19768354.2022.2091019

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