Triptolide and l-ascorbate palmitate co-loaded micelles for combination therapy of rheumatoid arthritis and side effect attenuation

Triptolide (TP) has its unique curative effect in the treatment of rheumatoid arthritis (RA), but its application is limited by the poor water solubility and multi-organ toxicity. We herein developed a novel nanoparticle platform composed of L-ascorbate palmitate (VP, vitamin C derivative) that can...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Man, Wang, Guoqiang, Yan, Yinyin, Jiang, Mengyuan, Wang, Zhirong, Zhang, Zhenqiang, Wu, Xiangxiang, Zeng, Huahui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9423844/
https://www.ncbi.nlm.nih.gov/pubmed/35999774
http://dx.doi.org/10.1080/10717544.2022.2115162

Ejemplares similares

Ejemplares similares