Disease-related blood-based differential methylation in cystic fibrosis and its representation in lung cancer revealed a regulatory locus in PKP3 in lung epithelial cells

Cystic fibrosis (CF) is a monogenic disease, characterized by massive chronic lung inflammation. The observed variability in clinical phenotypes in monozygotic CF twins is likely associated with the extent of inflammation. This study sought to investigate inflammation-related aberrant DNA methylatio...

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Detalles Bibliográficos
Autores principales: Schamschula, Esther, Lahnsteiner, Angelika, Assenov, Yassen, Hagmann, Wolfgang, Zaborsky, Nadja, Wiederstein, Markus, Strobl, Anna, Stanke, Frauke, Muley, Thomas, Plass, Christoph, Tümmler, Burkhard, Risch, Angela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9423854/
https://www.ncbi.nlm.nih.gov/pubmed/34415821
http://dx.doi.org/10.1080/15592294.2021.1959976

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