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An adjuvant-containing cDC1-targeted recombinant fusion vaccine conveys strong protection against murine melanoma growth and metastasis

Type 1 conventional dendritic cells (cDC1) efficiently cross-present antigens that prime cytotoxic CD8(+) T cells. cDC1 therefore constitute conceivable targets in cancer vaccine development. We generated recombinant fusion cancer vaccines that aimed to concomitantly deliver tumor antigen and adjuva...

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Detalles Bibliográficos
Autores principales:	Arabpour, Mohammad, Paul, Sanchari, Grauers Wiktorin, Hanna, Kaya, Mustafa, Kiffin, Roberta, Lycke, Nils, Hellstrand, Kristoffer, Martner, Anna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2022
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9423856/ https://www.ncbi.nlm.nih.gov/pubmed/36046810 http://dx.doi.org/10.1080/2162402X.2022.2115618

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