Correlation between Clinical and Wastewater SARS-CoV-2 Genomic Surveillance, Oregon, USA

SARS-CoV-2 variant proportions in a population can be estimated through genomic sequencing of clinical specimens or wastewater samples. We demonstrate strong pairwise correlation between statewide variant estimates in Oregon, USA, derived from both methods (correlation coefficient 0.97). Our results...

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Detalles Bibliográficos
Autores principales: Kaya, Devrim, Falender, Rebecca, Radniecki, Tyler, Geniza, Matthew, Cieslak, Paul, Kelly, Christine, Lininger, Noah, Sutton, Melissa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2022
Materias:
Research Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9423899/
https://www.ncbi.nlm.nih.gov/pubmed/35840124
http://dx.doi.org/10.3201/eid2809.220938
Descripción
Sumario:SARS-CoV-2 variant proportions in a population can be estimated through genomic sequencing of clinical specimens or wastewater samples. We demonstrate strong pairwise correlation between statewide variant estimates in Oregon, USA, derived from both methods (correlation coefficient 0.97). Our results provide crucial evidence of the effectiveness of community-level genomic surveillance.

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