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Costs of Tuberculosis at 3 Treatment Centers, Canada, 2010–2016

We estimated costs of managing different forms of tuberculosis (TB) across Canada by conducting a retrospective chart review and cost assessment of patients treated for TB infection, drug-susceptible TB (DS TB), isoniazid-resistant TB, or multidrug-resistant TB (MDR TB) at 3 treatment centers. We in...

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Detalles Bibliográficos
Autores principales: Campbell, Jonathon R., Nsengiyumva, Placide, Chiang, Leslie Y., Jamieson, Frances, Khadawardi, Hadeel, Mah, Henry K.-H., Oxlade, Olivia, Rasberry, Hayden, Rea, Elizabeth, Romanowski, Kamila, Sabur, Natasha F., Sander, Beate, Uppal, Aashna, Johnston, James C., Schwartzman, Kevin, Brode, Sarah K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9423918/
https://www.ncbi.nlm.nih.gov/pubmed/35997366
http://dx.doi.org/10.3201/eid2809.220092
Descripción
Sumario:We estimated costs of managing different forms of tuberculosis (TB) across Canada by conducting a retrospective chart review and cost assessment of patients treated for TB infection, drug-susceptible TB (DS TB), isoniazid-resistant TB, or multidrug-resistant TB (MDR TB) at 3 treatment centers. We included 90 patients each with TB infection and DS TB, 71 with isoniazid-resistant TB, and 62 with MDR TB. Median per-patient costs for TB infection (in 2020 Canadian dollars) were $804 (interquartile range [IQR] $587–$1,205), for DS TB $12,148 (IQR $4,388–$24,842), for isoniazid-resistant TB $19,319 (IQR $7,117–$41,318), and for MDR TB $119,014 (IQR $80,642–$164,015). Compared with costs for managing DS TB, costs were 11.1 (95% CI 9.1–14.3) times lower for TB infection, 1.7 (95% CI 1.3–2.1) times higher for isoniazid-resistant TB, and 8.1 (95% CI 6.1–10.6) times higher for MDR TB. Broadened TB infection treatment could avert high costs associated with managing TB disease.