Experimental Infection of Peromyscus Species Rodents with Sin Nombre Virus

We demonstrate that 6 distinct Peromyscus rodent species are permissive to experimental infection with Sin Nombre orthohantavirus (SNV). Viral RNA and SNV antibodies were detected in members of all 6 species. P. leucopus mice demonstrated markedly higher viral and antibody titers than P. maniculatus...

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Detalles Bibliográficos
Autores principales: Quizon, Kaye, Holloway, Kimberly, Iranpour, Mahmood, Warner, Bryce M., Deschambault, Yvon, Soule, Geoff, Tierney, Kevin, Kobasa, Darwyn, Sloan, Angela, Safronetz, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2022
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9423932/
https://www.ncbi.nlm.nih.gov/pubmed/35997624
http://dx.doi.org/10.3201/eid2809.220509
Descripción
Sumario:We demonstrate that 6 distinct Peromyscus rodent species are permissive to experimental infection with Sin Nombre orthohantavirus (SNV). Viral RNA and SNV antibodies were detected in members of all 6 species. P. leucopus mice demonstrated markedly higher viral and antibody titers than P. maniculatus mice, the established primary hosts for SNV.

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